Johannes R Lemke Selected Research

Ligands

1/2018

De novo mutations in GRIN1 cause extensive bilateral polymicrogyria.

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Johannes R Lemke Research Topics

Disease

14	Epilepsy (Aura) 10/2022 - 12/2012
10	Brain Diseases (Brain Disorder) 01/2021 - 04/2015
7	Neurodevelopmental Disorders 01/2022 - 01/2017
7	Seizures (Absence Seizure) 01/2019 - 12/2012
4	Epileptic Syndromes 09/2016 - 11/2013
3	Nervous System Diseases (Neurological Disorders) 03/2021 - 11/2018
3	Infantile Spasms (West Syndrome) 03/2020 - 01/2014
2	Partial Epilepsies (Epilepsy, Partial) 01/2022 - 01/2014
2	Obesity 01/2021 - 05/2017
2	Atrophy 03/2020 - 09/2017
2	Status Epilepticus (Complex Partial Status Epilepticus) 01/2019 - 10/2016
2	Temporal Lobe Epilepsy 09/2015 - 06/2015
2	Fever (Fevers) 12/2014 - 11/2013
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 11/2013 - 12/2012
1	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 10/2022
1	Microcephaly 10/2022
1	Ichthyosis (Xeroderma) 01/2022
1	Neuroblastoma 01/2022
1	Skin Diseases (Skin Disease) 01/2022
1	Acquired Immunodeficiency Syndrome (AIDS) 11/2021
1	Lipoma (Lipomata) 01/2021
1	Fragile X Syndrome (Martin Bell Syndrome) 01/2021
1	Focal Cortical Dysplasia 01/2019
1	Respiratory Insufficiency (Respiratory Failure) 01/2019
1	Brain Edema (Cerebral Edema) 01/2019
1	Leukoencephalopathies 10/2018
1	Hypogonadism (Hypergonadotropic Hypogonadism) 04/2018
1	Polymicrogyria 01/2018
1	Paraplegia (Spastic Paraplegia) 01/2018
1	Morbid Obesity 05/2017
1	Neoplasms (Cancer) 04/2017
1	GM1 Gangliosidosis (Gangliosidosis GM1) 03/2017
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 03/2017
1	Mucopolysaccharidosis IV (Morquio Syndrome) 03/2017
1	Mucolipidoses (Sialidosis) 03/2017
1	Neuraminidase deficiency with beta-galactosidase deficiency 03/2017
1	Neuraminidase 1 deficiency 03/2017
1	Ataxia (Dyssynergia) 01/2017
1	Movement Disorders (Movement Disorder) 01/2017
1	Intellectual Disability (Idiocy) 01/2017
1	Convulsions benign familial neonatal dominant form 09/2016
1	Idiopathic Generalized Epilepsy 09/2015
1	Febrile Seizures (Febrile Seizure) 12/2014
1	Type 2 Episodic Ataxia 12/2013
1	Cognitive Dysfunction 11/2013

Drug/Important Bio-Agent (IBA)

6	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2019 - 01/2014
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2014
3	Anticonvulsants (Antiepileptic Drugs)IBA 05/2017 - 12/2012
2	Sodium Channel BlockersIBA 01/2022 - 05/2017
2	RNA (Ribonucleic Acid)IBA 11/2021 - 01/2021
2	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 03/2021 - 09/2016
2	NucleotidesIBA 01/2021 - 03/2020
2	Voltage-Gated Sodium ChannelsIBA 11/2019 - 05/2017
2	Potassium Channels (Potassium Channel)IBA 01/2018 - 06/2017
2	Ion Channels (Ion Channel)IBA 10/2017 - 01/2014
2	SodiumIBA 05/2017 - 12/2012
2	Sodium Channels (Sodium Channel)IBA 05/2017 - 12/2012
1	Tryptophan-tRNA LigaseIBA 10/2022
1	Ligases (Synthetase)IBA 10/2022
1	Transfer RNA (tRNA)IBA 10/2022
1	Tetrodotoxin (Tetradotoxin)IBA 01/2022
1	Lipoxygenase (Lipoxygenase-1)IBA 01/2022
1	gamma-Aminobutyric Acid (GABA)IBA 01/2022
1	PotassiumIBA 03/2021
1	LipidsIBA 01/2021
1	AsparagineIBA 01/2021
1	human PRRT2 proteinIBA 10/2020
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2019
1	GlutaminaseIBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Cyclic NucleotidesIBA 11/2018
1	Biomarkers (Surrogate Marker)IBA 10/2018
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 04/2018
1	LigandsIBA 01/2018
1	Adenosine Monophosphate (AMP)IBA 01/2018
1	SpectrinIBA 09/2017
1	VitaminsIBA 06/2017
1	Deubiquitinating EnzymesIBA 04/2017
1	OligosaccharidesIBA 03/2017
1	Lysergic Acid Diethylamide (LSD)IBA 03/2017
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 03/2017
1	Ketamine FDA LinkGeneric 10/2016
1	MagnesiumIBA 10/2016
1	NAV1.1 Voltage-Gated Sodium ChannelIBA 01/2016
1	Immunoglobulin E (IgE)IBA 09/2015
1	GalaninIBA 06/2015
1	NeuropeptidesIBA 06/2015
1	Kv1.2 Potassium ChannelIBA 04/2015
1	Syntaxin 1IBA 12/2014
1	N-Methylaspartate (NMDA)IBA 01/2014
1	Glutamic Acid (Glutamate)FDA Link 01/2014
1	voltage-dependent calcium channel (P-Q type)IBA 12/2013
1	Q-Type Calcium Channels (Q-Type Calcium Channel)IBA 12/2013

Therapy/Procedure

6	Therapeutics 10/2022 - 11/2013
4	Precision Medicine 10/2022 - 10/2016
1	Electrodes (Electrode) 01/2018
1	Ligation 05/2017